Kanamycin sulfate

(HB4429)
Technical documents: SDS CoA Datasheet
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Product overview

Name Kanamycin sulfate
Description Protein synthesis inhibitor. Broad spectrum antibiotic.
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Biological Data

Biological description

Broad spectrum antibiotic which binds to the 30S subunit of the bacterial ribosome to inhibit protein synthesis.

Widely used as a selection marker for cells transformed with kanamycin B resistance gene.

Application notes
  • Used at 50µg/ml to selectively culture E. coli transfected with plasmids conferring kanamycin resistance

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (75 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Chemical name (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-bis(azanyl)-3-[(2S,3R,4S,5S,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-2-oxidanyl-cyclohexyl]oxy-oxane-3,4,5-triol sulphate
Molecular Weight 582.58
Chemical structure Kanamycin sulfate [25389-94-0] Chemical Structure
Molecular Formula C18H36N4O11 .H2O4S
CAS Number 25389-94-0
PubChem identifier 441374
SMILES C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N.OS(=O)(=O)O
InChi InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1
InChiKey QRRMITCICIMIDC-UHFFFAOYSA-N
MDL number MFCD00070253
Appearance White to off-white

References for Kanamycin sulfate

References are publications that support the biological activity of the product
  • The Effect of Kanamycin and Tetracycline on Growth and Photosynthetic Activity of Two Chlorophyte Algae

    Bashir et al (2016) Biomed Res Int. : 5656304

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