Stem cells are unspecialized cells that are capable of self-renewal through mitotic cell division. They may be induced to form more specialized cells by a process termed cellular differentiation.The main types of stems cells are embryonic stem cells (ESCs) found in blastocysts; adult (or somatic) stem cells, found in adult tissues, induced pluripotent stem cells (iPSCs) and cancer stem cells (CSCs). Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These tools can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on stem cell research tools from Hello Bio - they are around half the price of other suppliers.
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(+)-Abscisic acid (HB4674)Description:
Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligandPurity:
AMD 3100 octahydrochloride (HB2739)Description:
Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.
CHIR 99021 (HB1261)Description:
Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.Purity:
CHIR 99021 trihydrochloride (HB1262)Description:
Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.Purity:
Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.Purity:
Dexamethasone (water-soluble) (HB6020)Description:
Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture.Purity:
FK 506 (HB0289)Description:
Potent calcineurin phosphatase 2B inhibitor. Enhances osteoblastic differentiation in mesenchymal cells.Purity: