Angiotensin II is a peptide endocrine hormone which is involved in a variety of biological processes.
Angiotensin II is the primary effector of the RAS (renin-angiotensin system) which is a central component of the physiological/ pathophysiological responses of the cardiovascular system.
Stimulation with angiotensin II modulates blood pressure and regulates vasoconstriction and salt/water homeostasis.
Angiotensin II is also associated with induction of smooth muscle cell growth.
Angiotensin II is also involved in the inflammatory process. It is considered a growth factor that regulates cell growth and fibrosis. It increases adhesion molecules, cytokines and chemokines and exerts a proinflammatory effect on various cell types (e.g. leucocytes, endothelial cells and vascular smooth muscle cells).
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.
![Angiotensin II (human) [4474-91-3] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb2926_1.png "Angiotensin II (human) [4474-91-3]")
Understanding purity and quality - a guide for life scientists
