Angiotensin II is a peptide endocrine hormone which is involved in a variety of biological processes.
Angiotensin II is the primary effector of the RAS (renin-angiotensin system) which is a central component of the physiological/ pathophysiological responses of the cardiovascular system.
Stimulation with angiotensin II modulates blood pressure and regulates vasoconstriction and salt/water homeostasis.
Angiotensin II is also associated with induction of smooth muscle cell growth.
Angiotensin II is also involved in the inflammatory process. It is considered a growth factor that regulates cell growth and fibrosis. It increases adhesion molecules, cytokines and chemokines and exerts a proinflammatory effect on various cell types (e.g. leucocytes, endothelial cells and vascular smooth muscle cells).
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.