Actinomycin D

(HB1477)
Technical documents: SDS CoA Datasheet
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Product overview

Name Actinomycin D
Purity >98%
Description RNA polymerase inhibitor. Apoptosis inducer.
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Biological Data

Biological description RNA polymerase inhibitor and RNA synthesis inhibitor. DNA intercalating agent. Shows antitumor and cytotoxic effects. Also induces apoptosis.

Solubility & Handling

Solubility overview Soluble in DMSO (50 mM)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
Molecular Weight 1255.43
Molecular Formula C62H86N12O16
CAS Number 50-76-0
PubChem identifier 2019
SMILES CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
InChiKey RJURFGZVJUQBHK-LIAOQTPJSA-N
MDL number MFCD00005033
Appearance Red shiny crystals