Stem cells are unspecialized cells that are capable of self-renewal through mitotic cell division. They may be induced to form more specialized cells by a process termed cellular differentiation.The main types of stems cells are embryonic stem cells (ESCs) found in blastocysts; adult (or somatic) stem cells, found in adult tissues, induced pluripotent stem cells (iPSCs) and cancer stem cells (CSCs). Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These tools can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on stem cell research tools from Hello Bio - they are around half the price of other suppliers.
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(+)-Abscisic acid (HB4674)Description:
Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligandPurity:
AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.Purity:
L-Ascorbic acid (HB1238)Description:
Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.Purity:
DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.Purity:
Recombinant human BDNF protein (HB3485)Description:
Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.
CCG 1423 (HB3389)Description:
Rho/SRF pathway inhibitor. Induces intermediate mesoderm differentiation from ESCs.Purity:
Compound E (HB3849)Description:
Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.Purity:
Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.Purity: