Stem cells are unspecialized cells that are capable of self-renewal through mitotic cell division. They may be induced to form more specialized cells by a process termed cellular differentiation.The main types of stems cells are embryonic stem cells (ESCs) found in blastocysts; adult (or somatic) stem cells, found in adult tissues, induced pluripotent stem cells (iPSCs) and cancer stem cells (CSCs). Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These tools can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on stem cell research tools from Hello Bio - they are around half the price of other suppliers.
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Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.Purity:
AMD 3100 octahydrochloride (HB2739)Description:
Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.
L-Ascorbic acid (HB1238)Description:
Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.Purity:
DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.Purity:
Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.Purity:
BIX 01294 (HB1413)Description:
Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.Purity:
CCG 1423 (HB3389)Description:
Rho/SRF pathway inhibitor. Induces intermediate mesoderm differentiation from ESCs.Purity:
CHIR 99021 (HB1261)Description:
Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.Purity: