PI3K/Akt/mTOR

Potent, reversible AMPK activator. Inhibits MSC proliferation.

Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.

Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.

Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand

Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.

DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.

Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.

Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.