Cytokine Storm / Immune response signaling

Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.

View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling

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  1. Pack:
    10mg
    Price:
    $209
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    Pack:
    50mg
    Price:
    $746
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  2. NSC 74859 (HB1436)

    Description:

    Selective STAT3 inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $112
    Qty:
    Pack:
    25mg
    Price:
    $447
    Qty:
  3. Pam2CSK4 (HB3086)

    Description:

    TLR2/6 activator. Induces potent NF-κB activation and cytokine production.

    Pack:
    1mg
    Price:
    $157
    Qty:
  4. Pam3CSK4 (HB3428)

    Description:

    TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.

    Pack:
    1mg
    Price:
    $147
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  5. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
    Price:
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    Pack:
    2mg
    Price:
    $28
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    Pack:
    5×2mg
    Price:
    $115
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    Pack:
    10mg
    Price:
    $109
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    Pack:
    50mg
    Price:
    $308
    Qty:
  6. Pack:
    1mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $100
    Qty:
    Pack:
    50mg
    Price:
    $448
    Qty:
  7. 2  Reviews
    Top Reviews:
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    Description:

    PKC activator. Widely used for THP-1 cell differentiation and with ionomycin for stimulating cytokine production

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $65
    Qty:
    Pack:
    5mg
    Price:
    $215
    Qty:
    Pack:
    10mg
    Price:
    $395
    Qty:
    Pack:
    25mg
    Price:
    $774
    Qty:
  8. Pack:
    10mg
    Price:
    $116
    Qty:
    Pack:
    50mg
    Price:
    $414
    Qty:
  9. Description:

    Potent dual PI3-K/mTOR inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $109
    Qty:
    Pack:
    10mg
    Price:
    $211
    Qty:
    Pack:
    50mg
    Price:
    $823
    Qty:
  10. Pack:
    1mg
    Price:
    $114
    Qty:
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