Product overview

Name PI 103 hydrochloride
Description Potent dual PI3-K/mTOR inhibitor
Purity >98%
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Biological Data

Biological description Potent dual PI3-K/mTOR inhibitor with selectivity for PI3K family (IC 50 values are 2, 3, 3 and 15 nM at p110α, p110β, p110δ and p110γ and 20 and 83 nM at mTORC1 and mTORC2 respectively). Also shows activity at DNA-PK (IC50 = 14 nM). Shows antitumor activity and inhibits tumor cell invasion. Active in vivo.

Solubility & Handling

Storage instructions +4°C (desiccate)
Storage buffer Soluble in DMSO (20mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Chemical name 3-[4-(4-Morpholinylpyrido[3',2':4,5]f uro[3,2-d]pyrimidin-2-yl]phenol hydrochloride
Molecular Weight 384.82
Molecular Formula C19H16N4O3.HCl
CAS Number 371935-79-4
PubChem identifier 16739368
SMILES OC1=CC(C(N=C4N5CCOCC5)=NC3=C4OC2=NC=CC=C23)=CC=C1.Cl
InChiKey XSQMYBFFYPTMFE-UHFFFAOYSA-N