Chemogenetics
Chemogenetics research involves the use of small molecule ligands that selectively target genetically-modified receptors (Designer Receptors Exclusively Activated by Designer Drugs or DREADDs) or chimeric ion channels (Pharmacologically Selective Actuator Modules or PSAMs) to modulate and control neuronal activity. Researchers can save up to 50% on chemogenetics research products from Hello Bio – they are up to half the price of other suppliers and have been reviewed and cited by researchers worldwide.
View products: DREADDs | PSEMS | CATKLAMP View Resources: DREADDs Mini-Review | DREADDs for studying GPCRs
- Description:
Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Water soluble.
Purity:>98%
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Tropisetron hydrochloride (HB2827)
Description:Potent 5-HT3 receptor antagonist. Also α7 nAChR partial agonist. Activates α7Q79G-GlyR chimeric ion channels.
Purity:>99%
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uPSEM792 hydrochloride (HB8542)
Description:Ultrapotent PSEM agonist for PSAM4-GlyR and PSAM4-5HT3. Brain penetrant.
Purity:>99%
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uPSEM817 tartrate (HB8620)
Description:Selective, ultrapotent PSEM agonist for PSAM4-GlyR and PSAM4-5HT3. Brain penetrant.
Purity:>99%
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Varenicline tartrate (HB2070)
Description:Selective α4β2 nAChR partial agonist; orally active
Purity:>99%
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Diphenhydramine hydrochloride (DPH) (HB2617)
Description:Histamine H1 antagonist. Potent actuator of a modified hM4Di "GRANPA" DREADD receptor.
Purity:>99%
