Chemogenetics
Chemogenetics research involves the use of small molecule ligands that selectively target genetically-modified receptors (e.g. Designer Receptors Exclusively Activated by Designer Drugs or DREADDs) or chimeric ion channels (Pharmacologically Selective Actuator Modules or PSAMs) to modulate and control neuronal activity. Researchers can save up to 50% on chemogenetics research products from Hello Bio – they are up to half the price of other suppliers and have been reviewed and cited by researchers worldwide.
View products: DREADDs | Peripherally restricted DREADD | PSEMS | CATKLAMP  View Resources: DREADDs Mini-Review | DREADDs for studying GPCRs
DREADD agonist 21 (Compound 21) (HB4888)
Description:Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant.
Purity:>98%
- Description:
Novel, selective activator of the peripherally restricted HCAD DREADD. Does not cross the BBB.
Purity:>99%
- Description:
Novel, selective activator of the peripherally restricted HCAD DREADD. Does not cross the BBB. Water soluble.
Purity:>98%
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Iperoxo (HB9785)
Description:Potent muscarinic acetylcholine receptor superagonist. Also binds the hM3R-miniGq DREADD receptor.
Purity:>99%
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Ivermectin (IVM) (HB1958)
Description:α7 nicotinic acetylcholine receptor positive allosteric modulator. Activates GluCI/GlyCI chemogenetic channels. Shows antiviral activity.
Purity:>95%
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JHU37152 (DREADD ligand) (HB6252)
Description:Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.
Purity:>98%
- Description:
Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.
Purity:>98%
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JHU37160 (DREADD ligand) (HB6260)
Description:Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.
Purity:>98%
- Description:
Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.
Purity:>98%
![FCH-2296413 sodium salt (Peripherally restricted HCAD DREADD actuator) [Water Soluble]](https://cdn.hellobio.com/media/catalog/product/cache/7630ee9852b6c22c7de1165054afc779/h/b/hb10013.png)
