Biochemicals & small molecules

Potent group III mGluR antagonist

mGlu_1α / mGlu_5a agonist

Potent, selective mGlu_8a agonist

Selective group I mGlu receptor agonist. Induces LTD.

Selective group I (mGluR₁ / mGluR₅) agonist

Group I / II mGlu antagonist

Potent, selective, non-competitive mGlu₅ antagonist

Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

Potent, selective, non-competitive mGlu₁ antagonist

Potent, highly selective mGlu_1a antagonist. Water soluble.