(S)-3,4-DCPG

Name: (S)-3,4-DCPG
Brand: Hello Bio
SKU: HB0044
Price: 34 USD
Availability: InStock

(HB0044)

Be the first to add a publication

Technical documents: SDS Datasheet

Product overview

Name

(S)-3,4-DCPG

Alternative names

(S)-3,4-Dicarboxyphenylglycine; UBP1109

Purity

>95%

Description

Potent, selective mGlu_8a agonist

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (3) References (4) Frequently bought together

Write Your Own Review

Biological Data

Biological description

Potent and selective mGlu_8a receptor agonist (EC₅₀ = 31 nM). Selective for mGlu_8a receptor over mGlu_1-7 receptors (EC₅₀ / IC₅₀ values are >3.5 µM). Shows neuroprotective, anti-cataleptic and anticonvulsant actions.

Solubility & Handling

Storage instructions

Room temperature (desiccate)

Solubility overview

Soluble in water (100mM)

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>95%

Chemical name

(S)-3,4-Dicarboxyphenylglycine

Molecular Weight

239.18

Chemical structure

Molecular Formula

C₁₀H₉NO₆

CAS Number

201730-11-2

PubChem identifier

16062593

SMILES

OC(=O)c1cc(ccc1C(=O)O)[C@H](N)C(=O)O

InChi

InChI=1S/C10H9NO6/c11-7(10(16)17)4-1-2-5(8(12)13)6(3-4)9(14)15/h1-3,7H,11H2,(H,12,13)(H,14,15)(H,16,17)/t7-/m0/s1

InChiKey

IJVMOGKBEVRBPP-ZETCQYMHSA-N

Technical guides

Metabotropic glutamate receptor (mGluR) mini-review

mGlu receptor (mGluR) associated proteins mini-review

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for (S)-3,4-DCPG

References are publications that support the biological activity of the product

Neuroprotective effects of metabotropic glutamate receptor group II and III activators against MPP(+)-induced cell death in human neuroblastoma SH-SY5Y cells: the impact of cell differentiation state.
Jantas D et al (2014) Neuropharmacology 83 : 36-53.
Read more (PubMedID: 24713472)
The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease.
Johnson KA et al (2013) Neuropharmacology 66 : 187-95.
Read more (PubMedID: 22546615)
Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid.
Folbergrová J et al (2008) Neuropharmacology 54(4) : 665-75.
Read more (PubMedID: 18191956)
(S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord.
Thomas NK et al (2001) Neuropharmacology 40(3) : 311-8.
Read more (PubMedID: 11166323)

Grouped product items
Order: HB0044
Pack	Price	Qty
50mg	$835
1mg	$34
5mg	$131
10mg	$215

Request bulk discount

Potent, selective mGlu_8a agonist

New Products in this Area

Pexidartinib (PLX3397)

HB8991

Potent CSF-1R inhibitor. Widely used microglia-depletion agent.

(S)-3,4-DCPG

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for (S)-3,4-DCPG

Neuroprotective effects of metabotropic glutamate receptor group II and III activators against MPP(+)-induced cell death in human neuroblastoma SH-SY5Y cells: the impact of cell differentiation state.

The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease.

Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid.

(S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord.

About you

Tell us about your publication!

Captcha

New Products in this Area

(S)-3,4-DCPG

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for (S)-3,4-DCPG

Neuroprotective effects of metabotropic glutamate receptor group II and III activators against MPP(+)-induced cell death in human neuroblastoma SH-SY5Y cells: the impact of cell differentiation state.

The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease.

Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid.

(S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord.

About you

Tell us about your publication!

Captcha

About you

How can we help you?

New Products in this Area

Related Products