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E4CPG

(HB0268)
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Product overview

Name E4CPG
Purity >98%
Description Group I / II mGlu antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (3) Reviews References (3) Frequently bought together
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Biological Data

Biological description Group I / II mGluR antagonist. Shows neuroprotective actions against glucocorticoid-mediated apoptosis.

Solubility & Handling

Solubility overview Soluble in NaOH(aq) (100mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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More Info

Dilution

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Chemical Data

Purity >98%
Chemical name (RS)-α-Ethyl-4-carboxyphenylglycine
Molecular Weight 223.23
Chemical structure E4CPG [170846-89-6] Chemical Structure
Molecular Formula C11H13NO4
CAS Number 170846-89-6
PubChem identifier 3937355
SMILES NC(C(O)=O)(CC)C1=CC=C(C(O)=O)C=C1
InChi InChI=1S/C11H13NO4/c1-2-11(12,10(15)16)8-5-3-7(4-6-8)9(13)14/h3-6H,2,12H2,1H3,(H,13,14)(H,15,16)
InChiKey AIEFWRHRHFRLFT-UHFFFAOYSA-N
MDL number MFCD01074798

References for E4CPG

References are publications that support the biological activity of the product

  • Ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic N-methyl-D-aspartate receptors.

    Lu J et al (2003) Neuroscience 121(1) : 123-31.
    Read more (PubMedID: 12946705)

  • Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.

    Sekiyama N et al (1996) Br J Pharmacol 117(7) : 1493-503.
    Read more (PubMedID: 8730745)

  • Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs).

    Bedingfield JS et al (1995) Br J Pharmacol 116(8) : 3323-9.
    Read more (PubMedID: 8719814)

3 Item(s)

Grouped product items
Order: HB0268
Pack PriceQty
5mg
$69
10mg
$124
25mg
$274
50mg
$480
Group I / II mGlu antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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