My Cart
My account
Menu
Main Menu

CPPG

(HB0217)
Be the first to add a publication
Technical documents: SDS CoA Datasheet
Be the first to review this product
Add to Wish List

Product overview

Name CPPG
Purity >98%
Description Potent group III mGluR antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (3) Reviews References (3) Frequently bought together
Write Your Own Review
You're reviewing:CPPG
Rate this item:

Images

CPPG product vial image | Hello Bio
CPPG product vial image | Hello Bio

CPPG product vial image | Hello Bio

CPPG product vial image | Hello Bio

Biological Data

Biological description Potent mGlu receptor antagonist. Shows 20-fold selectivity for group III compared to group II mGlu receptors (IC50 values are 2.2 and 46.3 nM respectively). Less potent antagonist at group I mGlu receptors.

Solubility & Handling

Solubility overview Soluble in NaOH(aq) (100mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >98%
Chemical name (RS)-α-Cyclopropyl-4-phosphonophenyl glycine
Molecular Weight 271.21
Chemical structure CPPG [183364-82-1] Chemical Structure
Molecular Formula C11H14NO5P
CAS Number 183364-82-1
PubChem identifier 2878
SMILES NC(C2CC2)(C(O)=O)C1=CC=C(P(O)(O)=O)C=C1
InChiKey IGODGTDUQSMDQU-UHFFFAOYSA-N

References for CPPG

References are publications that support the biological activity of the product

  • Antagonism of metabotropic glutamate receptor 4 receptors by (RS)-alpha-cyclopropyl-4-phosphonophenylglycine alters the taste of amino acids in rats.

    Eschle BK et al (2009) Neuroscience 163(4) : 1292-301.
    Read more (PubMedID: 19631258)

  • Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.

    Jane DE et al (1996) Neuropharmacology 35(8) : 1029-35.
    Read more (PubMedID: 9121605)

  • The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist.

    Toms NJ et al (1996) Br J Pharmacol 119(5) : 851-4.
    Read more (PubMedID: 8922731)

3 Item(s)

Related Products
Grouped product items
Order: HB0217
Pack PriceQty
10mg
$196
50mg
$766
Potent group III mGluR antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@hellobio.com

Related Products

(R,S)-3,5-DHPG
Code:
HB0026
Pack:
10mg, 50mg, 10mM (add 1ml water)
Price:
$121, $508, $103
Selective group I (mGluR1 / mGluR5) agonist
L-AP4
Code:
HB0370
Pack:
5mg, 10mg, 25mg, 50mg
Price:
$102, $197, $411, $816
(Free trial)
L-AP4 is a selective group III mGluR agonist which inhibits synaptic transmis...
MPEP hydrochloride
Code:
HB0426
Pack:
10mg, 50mg
Price:
$123, $458
Potent, selective mGluR5 antagonist / mGluR4 positive allosteric modulator