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CPPG

(HB0217)
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Technical documents: SDS CoA Datasheet

Product overview

Name CPPG
Purity >98%
Description Potent group III mGluR antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (3) Reviews References (3) Frequently bought together
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CPPG product vial image | Hello Bio
CPPG product vial image | Hello Bio

CPPG product vial image | Hello Bio

CPPG product vial image | Hello Bio

Biological Data

Biological description Potent mGlu receptor antagonist. Shows 20-fold selectivity for group III compared to group II mGlu receptors (IC50 values are 2.2 and 46.3 nM respectively). Less potent antagonist at group I mGlu receptors.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in NaOH(aq) (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name (RS)-α-Cyclopropyl-4-phosphonophenyl glycine
Molecular Weight 271.21
Chemical structure CPPG [183364-82-1] Chemical Structure
Molecular Formula C11H14NO5P
CAS Number 183364-82-1
PubChem identifier 2878
SMILES NC(C2CC2)(C(O)=O)C1=CC=C(P(O)(O)=O)C=C1
InChiKey IGODGTDUQSMDQU-UHFFFAOYSA-N

References for CPPG

References are publications that support the biological activity of the product

  • Antagonism of metabotropic glutamate receptor 4 receptors by (RS)-alpha-cyclopropyl-4-phosphonophenylglycine alters the taste of amino acids in rats.

    Eschle BK et al (2009) Neuroscience 163(4) : 1292-301.
    Read more (PubMedID: 19631258)

  • Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.

    Jane DE et al (1996) Neuropharmacology 35(8) : 1029-35.
    Read more (PubMedID: 9121605)

  • The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist.

    Toms NJ et al (1996) Br J Pharmacol 119(5) : 851-4.
    Read more (PubMedID: 8922731)

3 Item(s)

Related Products
Grouped product items
Order: HB0217
Pack PriceQty
10mg
$190
50mg
$744
Potent group III mGluR antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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