Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialized transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can make big savings on Hello Bio's Nuclear Receptors agonists, antagonists and modulators (e.g. tamoxifen, 4-OHT, fulvestrant, DPN, PPT), our prices are around 25-50% less than other suppliers.
View products: Aryl hydrocarbon receptor | Estrogen and related | Liver X and farnesoid X receptors (LXR/FXR) | Glucocorticoid Mineralocorticoid | Other | PPAR | Progesterone
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Rosiglitazone (HB2556)
Description:Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.
Purity:>99%
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Rosiglitazone maleate (HB4140)
Description:Potent and selective PPARγ agonist; antidiabetic agent.
Purity:>98%
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Spironolactone (HB2799)
Description:Mineralocorticoid and androgen receptor antagonist
Purity:>98%
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Stigmasterol (HB4095)
Description:Phytosterol with anticancer and many other biological actions. Farnesoid X receptor antagonist.
Purity:>95%
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T3 (triiodothyronine) (HB7470)
Description:Thyroid hormone. Frequently used in various stem cell protocols.
Purity:>98%
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Tamoxifen (HB0601)
Description:Estrogen receptor antagonist/ partial agonist. May be used in genome engineering (e.g. CreER/ CRISPR-Cas9).
Purity:>99%
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Tamoxifen Citrate (HB0602)
Description:Estrogen receptor antagonist/ partial agonist. May be used in genome engineering (e.g. CreER/ CRISPR-Cas9). Citrate salt.
Purity:>98%
