Product overview

Name Rosiglitazone
Alternative names BRL 49653
Purity >99%
Description Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.
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Biological Data

Biological description Potent and selective PPARγ agonist. Potent insulin sensitizing agent which binds PPAR receptors to fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance and shows antidiabetic, hypoglycemic and anti-inflammatory action. Also promotes mesenchymal stem cells (MSCs) adipocyte differentiation and enhances endogenous neural progenitor cells (NPCs) proliferation.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in 0.1M HCl (100 mM), and in DMSO (100 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >99%
Chemical name 5-[[4-[2-(Methyl-2-pyridinylamino)e thoxy]phenyl]methyl]-2,4-thiazolidinedione
Molecular Weight 357.43
Chemical structure Rosiglitazone [122320-73-4] Chemical Structure
Molecular Formula C18H19N3O3S
CAS Number 122320-73-4
PubChem identifier 77999
SMILES CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
InChi InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)
InChiKey YASAKCUCGLMORW-UHFFFAOYSA-N
MDL number MFCD00871760
Appearance White to off-white powder