Mineralocorticoid

Potent mGlu₄ positive allosteric modulator

mGlu₄ positive allosteric modulator

Potent mGlu₅ positive allosteric modulator

Potent 5-HT_1A receptor antagonist. D₄ receptor agonist.

Non-selective JAK3 inhibitor and potent EGFR inhibitor. Induces neural progenitor cell differentiation.

Serotonin/norepinephrine reuptake inhibitor (SNRI)

Endogenous group II mGlu agonist

Novel, selective mGlu₇ antagonist

K_ir3.4 channel activator

Guanylyl cyclase activator. Also induces G1 cell cycle arrest.