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Biological Data
| Biological description | Endogenous group II mGluR agonist. Displays apoptosis inducing properties and induces the exflagellation of Plasmodium microgametocytes. |
Solubility & Handling
| Storage instructions | Room temperature |
| Solubility overview | Soluble in DMSO (100mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 4,8-Dihydroxyquinoline-2-carboxylic acid |
| Chemical structure | ![Xanthurenic acid [59-00-7] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Xanthurenic acid [59-00-7]") |
| Molecular Formula | C10H7NO4 |
| SMILES | OC1=C2C(C(O)=CC(C(O)=O)=N2)=CC=C1 |
| InChiKey | FBZONXHGGPHHIY-UHFFFAOYSA-N |
References for Xanthurenic acid
References are publications that support the biological activity of the product
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Actions of Xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus.
Copeland CS et al (2013) Neuropharmacology 66 : 133-42. -
The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis.
Han Q et al (2007) J Insect Physiol 53(3) : 254-63. -
Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown.
Malina HZ et al (2001) BMC Physiol 1 : 7
Endogenous group II mGlu agonist
![Xanthurenic acid [59-00-7] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0659.png "Xanthurenic acid [59-00-7]")
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