My Cart
My account
Menu
Main Menu

VU 0364439

(HB0639)
Be the first to add a publication
Technical documents: Datasheet
Be the first to review this product
Add to Wish List

Product overview

Name VU 0364439
Purity >99%
Description Potent mGlu4 positive allosteric modulator
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (3) Reviews References (1)
Write Your Own Review
You're reviewing:VU 0364439
Rate this item:

Biological Data

Biological description Potent mGlu4 receptor positive allosteric modulator (EC50 = 19.8 nM).

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >99%
Chemical name N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide
Molecular Weight 422.29
Chemical structure VU 0364439 [1246086-78-1] Chemical Structure
Molecular Formula C18H13Cl2N3O3S
CAS Number 1246086-78-1
PubChem identifier 46934289
SMILES O=C(NC2=CC(Cl)=C(S(NC3=C(Cl)C=CC=C3)(=O)=O)C=C2)C1=NC=CC=C1
InChiKey IXHCGJXBIHHIEF-UHFFFAOYSA-N

References for VU 0364439

References are publications that support the biological activity of the product

  • Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS).

    Engers DW et al (2010) Bioorg Med Chem Lett 20(17) : 5175-8.
    Read more (PubMedID: 20667732)

1 Item

Related Products
Grouped product items
Order: HB0639
Pack PriceQty
50mg
$722
Potent mGlu4 positive allosteric modulator
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@hellobio.com

New Products in this Area

Pexidartinib (PLX3397)
HB8991

Potent CSF-1R inhibitor. Widely used microglia-depletion agent.

Related Products

(S)-3,5-DHPG
Code:
HB0045
Pack:
1mg, 5mg, 10mg, 50mM (add 1ml water)
Price:
$70, $116, $210, $264
Selective group I mGlu receptor agonist. Induces LTD.
MTEP hydrochloride
Code:
HB0431
Pack:
10mg, 50mg, 10mM (add 1ml water)
Price:
$128, $483, $50
Potent, highly selective, non-competitive mGluR5 antagonist
(R,S)-3,5-DHPG
Code:
HB0026
Pack:
10mg, 50mg, 10mM (add 1ml water)
Price:
$116, $487, $99
Selective group I (mGluR1 / mGluR5) agonist