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Spaglumic acid

(HB0585)
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Product overview

Name Spaglumic acid
Purity >98%
Description Selective mGlu3 agonist, peptide neurotransmitter
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (3) Reviews References (2) Frequently bought together
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Biological Data

Biological description Selective mGlu3 receptor agonist and endogenous mammalian peptide neurotransmitter. Blood-brain barrier permeable. Shows anti-allergic actions, potential analgesic and neuroprotective effects. Decreases social withdrawal and motor response in mouse models of schizophrenia.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name N-Acetyl-L-aspartyl-L-glutamic acid
Molecular Weight 304.26
Chemical structure Spaglumic acid [3106-85-2] Chemical Structure
Molecular Formula C11H16N2O8
CAS Number 3106-85-2
PubChem identifier 91873144
SMILES CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O.O
InChi InChI=1S/C11H16N2O8.H2O/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16;/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21);1H2/t6-,7-;/m0./s1
InChiKey LQMRHOYCEMZABM-LEUCUCNGSA-N
MDL number MFCD00076652
Appearance White solid

References for Spaglumic acid

References are publications that support the biological activity of the product

  • Comparative efficacy of topical antihistamines in an animal model of early phase allergic conjunctivitis.

    Sanchis-Merino ME et al (2008) Exp Eye Res 86(5) : 791-7.
    Read more (PubMedID: 18378229)

  • N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells.

    Wroblewska B et al (1997) J Neurochem 69(1) : 174-81.
    Read more (PubMedID: 9202308)

2 Item(s)

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Order: HB0585
Pack PriceQty
50mg
$133
Selective mGlu3 agonist, peptide neurotransmitter
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Hazardous: $35

Shipped on ice: $35

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