Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
DNQX disodium salt (HB0262)
Description:Selective, competitive AMPA / kainate receptor antagonist. Sodium salt.
Purity:>98%
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Eliprodil (HB0274)
Description:Non-competitive, GluN2B subunit selective NMDA receptor antagonist
Purity:>98%
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Evans blue (HB0280)
Description:Potent AMPA / kainate receptor antagonist. Vesicular L-glutamate uptake inhibitor.
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- Description:
Broad spectrum glutamate antagonist
Purity:>99%
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