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Images Evans blue product vial image | Hello Bio
Evans blue product vial image | Hello Bio Solubility & Handling Storage instructions Room temperature
Solubility overview Soluble in water (10mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4, 4'-diyl)bis(azo)bis [4-amino-5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt
Chemical structure
Molecular Formula C34 H24 N6 Na4 O14 S4
SMILES CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(C4=C(C=C3)C(=CC(=C4N)S(=O)(=O)[O-])S(=O)(=O)[O-])O)C)N=NC5=C(C6=C(C=C5)C(=CC(=C6N)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+].[Na+].[Na+]
InChiKey ATNOAWAQFYGAOY-UHFFFAOYSA-J
References for Evans blue References are publications that support the biological activity of the product
Uptake of L-glutamate into synaptic vesicles: competitive inhibition by dyes with biphenyl and amino- and sulphonic acid-substituted naphthyl groups. Roseth S et al (1998) Biochem Pharmacol 56(9) : 1243-9. Differential modulation of AMPA receptor mediated currents by evans blue in postnatal rat hippocampal neurones. Schürmann B et al (1997) Br J Pharmacol 121(2) : 237-47. P2-purinoceptor antagonists: II. Blockade of P2-purinoceptor subtypes and ecto-nucleotidases by compounds related to Evans blue and trypan blue. Wittenburg H et al (1996) Naunyn Schmiedebergs Arch Pharmacol 354(4) : 491-7. Evans blue antagonizes both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate receptors and modulates receptor desensitization. Price CJ et al (1996) Mol Pharmacol 50(6) : 1665-71.
Publications
These publications cite the use of Evans blue purchased from Hello Bio:
Platelet-like particles reduce coagulopathy-related and neuroinflammatory pathologies post-experimental traumatic brain injury Todd J et al (2021) J Biomed Mater Res B Appl Biomater 109(12) : 2268-2278
Potent AMPA / kainate receptor antagonist. Vesicular L-glutamate uptake inhibitor.
![Evans blue [314-13-6] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0280.png "Evans blue [314-13-6]")
Understanding purity and quality - a guide for life scientists
