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gamma-DGG / γ-DGG (γ-D-glutamylglycine)

(HB0680)
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Product overview

Name gamma-DGG / γ-DGG (γ-D-glutamylglycine)
Alternative names Gamma-D-glutamylglycine
Purity >99%
Description Broad spectrum glutamate antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (4) Reviews References (3) Frequently bought together
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γ-DGG (γ-D-glutamylglycine) product vial image | Hello Bio
γ-DGG (γ-D-glutamylglycine) product vial image | Hello Bio

γ-DGG (γ-D-glutamylglycine) product vial image | Hello Bio

γ-DGG (γ-D-glutamylglycine) product vial image | Hello Bio

Biological Data

Biological description

Broad spectrum glutamate antagonist. Low affinity, rapidly dissociating competitive AMPA receptor antagonist which blocks AMPAR-mediated EPSCs. Also an non-selective NMDA receptor antagonist. Shows anti-depressant actions.

Solubility & Handling

Solubility overview Soluble in NaOH(aq) (100mM, gentle warming) or water (100mM, gentle warming)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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More Info

Dilution

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More Info

Chemical Data

Purity >99%
Chemical name γ-D-Glutamylglycine
Molecular Weight 204.18
Chemical structure γ-DGG (γ-D-glutamylglycine) [6729-55-1] Chemical Structure
Molecular Formula C7H12N2O5
CAS Number 6729-55-1
PubChem identifier 6604701
SMILES O=C(CC[C@@H](N)C(=O)O)NCC(=O)O
InChiKey ACIJGUBIMXQCMF-SCSAIBSYSA-N

References for gamma-DGG / γ-DGG (γ-D-glutamylglycine)

References are publications that support the biological activity of the product

  • Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons.

    Guzman RE et al (2014) Front Cell Neurosci 8 : 143
    Read more (PubMedID: 24904288)

  • Glutamate neurotransmission in the cerebellar interposed nuclei: involvement in classically conditioned eyeblinks and neuronal activity.

    Aksenov DP et al (2005) J Neurophysiol 93(1) : 44-52.
    Read more (PubMedID: 15331619)

  • Depressant actions of gamma-D-glutamylaminomethyl sulfonate (GAMS) on amino acid-induced and synaptic excitation in the cat spinal cord.

    Davies J et al (1985) Brain Res 327(1-2) : 113-20.
    Read more (PubMedID: 3838689)

3 Item(s)

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Grouped product items
Order: HB0680
Pack PriceQty
50mg
$128
Broad spectrum glutamate antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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