Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
CP 465022 hydrochloride (HB0214)
Description:Potent, non-competitive AMPA receptor antagonist
Purity:>99%
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Cyclothiazide (HB0221)
Description:AMPA receptor positive allosteric modulator. Inhibits AMPAR desensitization.
Purity:>98%
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5,7-Dichlorokynurenic acid (HB0078)
Description:Potent, selective, competitive glycine site NMDA receptor antagonist
Purity:>98%
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Dihydroanatoxin-A fumarate (dhATX) (HB7494)
Description:Less toxic, degradation product of Anatoxin-A
Purity:>95% (NMR)
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