My Cart
My account
Menu
Main Menu

Etomidate

(HB0937)
Be the first to add a publication
Technical documents: SDS Datasheet
Be the first to review this product
Add to Wish List

Product overview

Name Etomidate
Purity >99%
Description Potent GABAA receptor positive allosteric modulator
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
Write Your Own Review
You're reviewing:Etomidate
Rate this item:

Images

Etomidate product vial image | Hello Bio
Etomidate product vial image | Hello Bio

Etomidate product vial image | Hello Bio

Etomidate product vial image | Hello Bio

Biological Data

Biological description Potent GABAA receptor positive allosteric modulator. Selective for β2 and β3 subunits (EC50 values are 0.6, 0.7 and 7.4 µM for α6β2γ2, α6β3γ2 and α6β1γ2 GABAA receptor subtypes respectively). Shows short acting hypnotic actions. Blood-brain barrier permeable.

Solubility & Handling

Solubility overview Soluble in ethanol (100mM) and in 1M HCl (50mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >99%
Chemical name (R)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester
Molecular Weight 244.29
Chemical structure Etomidate [33125-97-2] Chemical Structure
Molecular Formula C14H16N2O2
CAS Number 33125-97-2
PubChem identifier 36339
SMILES CCOC(=O)C1=CN=CN1C(C)C2=CC=CC=C2
InChi InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3
InChiKey NPUKDXXFDDZOKR-UHFFFAOYSA-N
MDL number MFCD00869295

References for Etomidate

References are publications that support the biological activity of the product

  • Distinct actions of etomidate and propofol at beta3-containing gamma-aminobutyric acid type A receptors.

    Drexler B et al (2009) Neuropharmacology 57(4) : 446-55.
    Read more (PubMedID: 19555700)

  • Etomidate and other non-barbiturates.

    Vanlersberghe C et al (2008) Handb Exp Pharmacol -182 : 267-82.
    Read more (PubMedID: 18175096)

  • The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid.

    Belelli D et al (1997) Proc Natl Acad Sci U S A 94(20) : 11031-6.
    Read more (PubMedID: 9380754)

3 Item(s)

Related Products
Grouped product items
Order: HB0937
Pack PriceQty
10mg
$111
50mg
$452
Potent GABAA receptor positive allosteric modulator
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@hellobio.com

Related Products

SR 95531 hydrobromide (Gabazine)
Code:
HB0901
Pack:
10mg, 50mg, 10mM (add 1ml water)
Price:
$107, $410, $69
(Free trial)
Selective, competitive GABAA receptor antagonist
(-)-Bicuculline methochloride
Code:
HB0895
Pack:
25mg, 50mg, 125mg
Price:
$199, $389, $715
Prototypic, competitive GABAA receptor antagonist
Picrotoxin
Code:
HB0506
Pack:
1g, 5x1g
Price:
$47, $202
Non-competitive GABAA receptor antagonist