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Images L-Glutamate product vial image | Hello Bio
L-Glutamate product vial image | Hello Bio Biological Data Biological description Predominant excitatory neurotransmitter in the CNS. Active at ionotropic and metabotropic glutamate receptors. Physiological roles in vivo. Also associated with neuronal cell death and neurodegenerative disease pathogensesis.
Solubility & Handling Storage instructions Room temperature
Solubility overview Soluble in 0.1M NaOH (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name (S )-1-Aminopropane-1,3-dicarboxylic acid
Chemical structure
Molecular Formula C5 H9 NO4
SMILES C(CC(=O)O)[C@@H](C(=O)O)N
InChi InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChiKey WHUUTDBJXJRKMK-VKHMYHEASA-N
References for L-Glutamate References are publications that support the biological activity of the product
Modulation of gene expression of adenosine and metabotropic glutamate receptors in rat's neuronal cells exposed to L-glutamate and [60]fullerene. Giust D et al (2014) J Biomed Nanotechnol 10(8) : 1610-9. Glutamate receptor-mediated inhibition of L-glutamate efflux from cerebral cortex in vitro. Hainsworth AH et al (2006) Brain Res 1114(1) : 36-40. Ionotropic and metabotropic glutamate receptor structure and pharmacology. Kew JN et al (2005) Psychopharmacology (Berl) 179(1) : 4-29.
Publications
These publications cite the use of L-Glutamate purchased from Hello Bio:
The autism-associated gene SYNGAP1 regulates human cortical neurogenesis Quadrato et al (2022) Biorxiv : https://doi.org/10.1101/2022.05.10.491244
Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks Crowe et al. (2020) Lab Chip. : 1
Glutamate receptor excitatory neurotransmitter
![L-Glutamate [56-86-0] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0383.png "L-Glutamate [56-86-0]")
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