Product overview

Name L-Glutamate
Description Glutamate receptor excitatory neurotransmitter
Alternative names L-glutamic acid
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Biological Data

Biological description Predominant excitatory neurotransmitter in the CNS. Active at ionotropic and metabotropic glutamate receptors. Physiological roles in vivo. Also associated with neuronal cell death and neurodegenerative disease pathogensesis.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in 0.1M NaOH (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Chemical name (S)-1-Aminopropane-1,3-dicarboxylic acid
Molecular Weight 147.13
Chemical structure Chemical structure
Molecular Formula C5H9NO4
CAS Number 56-86-0
PubChem identifier 33032
SMILES C(CC(=O)O)[C@@H](C(=O)O)N
InChi InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChiKey WHUUTDBJXJRKMK-VKHMYHEASA-N
MDL number MFCD00002634
Appearance White solid

References for L-Glutamate

References are publications that support the biological activity of the product
  • Modulation of gene expression of adenosine and metabotropic glutamate receptors in rat's neuronal cells exposed to L-glutamate and [60]fullerene.

    Giust D et al (2014) J Biomed Nanotechnol 10(8) : 1610-9.
  • Glutamate receptor-mediated inhibition of L-glutamate efflux from cerebral cortex in vitro.

    Hainsworth AH et al (2006) Brain Res 1114(1) : 36-40.
  • Ionotropic and metabotropic glutamate receptor structure and pharmacology.

    Kew JN et al (2005) Psychopharmacology (Berl) 179(1) : 4-29.
Publications
These publications cite the use of L-Glutamate purchased from Hello Bio:
  • Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks

    Crowe et al. (2020) Lab Chip. : 1
    PubMedID: 32314760

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