Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
Okadaic Acid (HB0468)
Description:Potent, non-competitive protein phosphatase inhibitor
Purity:>98%
Okadaic Acid Sodium Salt (HB0470)
Description:Water soluble, potent protein phosphatase 1 and 2A inhibitor
Purity:>98%
Olanzapine (HB1786)
Description:5-HT2A and D2 antagonist. Potent DREADD agonist. Atypical antipsychotic.
Purity:>99%
- Description:
LPA1 and LPA2 agonist. Inhibits differentiation of neural stem cells (NSCs) into neurons.
Purity:>95%
ω-Agatoxin IVA (HB1212)
Description:Potent, selective P-type / Q-type Ca2+ channel blocker
Purity:>95%