My Cart
My account
Menu
Main Menu

Oligomycin A

(HB4488)
Be the first to add a publication
Technical documents: SDS CoA Datasheet
Be the first to review this product
Add to Wish List

Product overview

Name Oligomycin A
Purity >98%
Description Inhibitor of mitochondrial function
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
Write Your Own Review
You're reviewing:Oligomycin A
Rate this item:

Biological Data

Biological description

Inhibitor of mitochondrial function which blocks the proton channel of mitochondrial ATP synthase to block oxidative phosphorylation and inhibit the electron transport chain.

Anti-tumor antibiotic.

Solubility & Handling

Solubility overview Soluble in ethanol (10 mM)
Storage instructions -20°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >98%
Chemical name (1R,4E,5'S,6S,6'S,7R,8S,10R,11R, 12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione
Molecular Weight 791.06
Molecular Formula C45H74O11
CAS Number 579-13-5
PubChem identifier 5281899
SMILES CC[C@H]\1CC[C@@H]2[C@@H]([C@@H]([C@H]([C@@]3(O2)CC[C@H]([C@H](O3)C[C@H](C)O)C)C)OC(=O)/C=C/[C@H]([C@@H]([C@H](C(=O)[C@H]([C@@H]([C@H](C(=O)[C@@]([C@@H]([C@H](C/C=C/C=C1)C)O)(C)O)C)O)C)C)O)C)C
InChiKey MNULEGDCPYONBU-MQCNKYSOSA-N
MDL number MFCD00065705
Appearance White to off-white

References for Oligomycin A

References are publications that support the biological activity of the product

  • Oligomycin A-induced Inhibition of Mitochondrial ATP-synthase Activity Suppresses Boar Sperm Motility and in Vitro Capacitation Achievement Without Modifying Overall Sperm Energy Levels

    Lluch et al (2014) Reprod Fertil Dev 26(6) : 883-97
    Read more (PubMedID: 25319379)

  • Assessing Mitochondrial Dysfunction in Cells

    Brand et al (2011) Biochem J 435(2) : 297-312
    Read more (PubMedID: 21726199)

  • Mechanism of Inhibition of Mitochondrial Adenosine Triphosphatase by Dicyclohexylcarbodiimide and Oligomycin: Relationship to ATP Synthesis

    Penefsky, (1985) Comparative Study 82(6) : 1589-93
    Read more (PubMedID: 2858849)

3 Item(s)

Related Products
Grouped product items
Order: HB4488
Pack PriceQty
5mg
$176
Inhibitor of mitochondrial function
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@hellobio.com

Related Products

CCCP
Code:
HB5062
Pack:
500mg
Price:
$98
(Free trial)
Potent uncoupler of mitochondrial oxidative phosphorylation
FCCP
Code:
HB2903
Pack:
10mg, 50mg
Price:
$92, $348
(Free trial)
Potent uncoupler of mitochondrial oxidative phosphorylation.
Rotenone
Code:
HB5398
Pack:
1g, 5x1g
Price:
$69, $191
Mitochondrial Complex I Inhibitor. Induces mitochondrial dysfunction.