PI3K/AKT/mTOR signaling inhibitor. Selectively reduces proliferative capacity of human melanoma BRAF(V600E) mutated cells. Also shows weak agonist activity at NK1 receptors and acts synergistically with rapamycin to enhance antiproliferative effects. Reduces tumor progression in vivo.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in PBS (1 mg/ml), and in DMSO
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists
