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Biological Data
Biological description | Phospholipase A2 (PLA2) inhibitor (IC50 = 1.4 µM). Also inhibits ATP-induced histamine release. Cell permeable. |
Solubility & Handling
Storage instructions | -20°C |
Solubility overview | Soluble in ethanol |
Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
Chemical structure | |
Molecular Formula | C25H52NO5P |
PubChem identifier | 5353846 |
SMILES | CCCCCCCCC=CCCCCCCCCOCCOP(=O)([O-])OCC[N+](C)(C)C |
References for Oleyloxyethyl Phosphorylcholine
References are publications that support the biological activity of the product
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ATP-induced histamine release is in part related to phospholipase A2-mediated arachidonic acid metabolism in rat peritoneal mast cells.
Lee YH et al (2001) Arch Pharm Res 24(6) : 552-6. -
A novel phospholipase A2 activity in saliva of the lone star tick, Amblyomma americanum (L.).
Bowman AS et al (1997) Exp Parasitol 87(2) : 121-32.