Oleyloxyethyl Phosphorylcholine

(HB0472)
Technical documents: Datasheet

Product overview

Name Oleyloxyethyl Phosphorylcholine
Purity >98%
Description PLA2 inhibitor
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Biological Data

Biological description Phospholipase A2 (PLA2) inhibitor (IC50 = 1.4 µM). Also inhibits ATP-induced histamine release. Cell permeable.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in ethanol
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 477.7
Chemical structure Oleyloxyethyl Phosphorylcholine  [84601-19-4] Chemical Structure
Molecular Formula C25H52NO5P
CAS Number 84601-19-4
PubChem identifier 5353846
SMILES CCCCCCCCC=CCCCCCCCCOCCOP(=O)([O-])OCC[N+](C)(C)C

References for Oleyloxyethyl Phosphorylcholine

References are publications that support the biological activity of the product
  • ATP-induced histamine release is in part related to phospholipase A2-mediated arachidonic acid metabolism in rat peritoneal mast cells.

    Lee YH et al (2001) Arch Pharm Res 24(6) : 552-6.
  • A novel phospholipase A2 activity in saliva of the lone star tick, Amblyomma americanum (L.).

    Bowman AS et al (1997) Exp Parasitol 87(2) : 121-32.

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