Group I (mGlu5, mGlu1)

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Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.

Items 711-720 of 1076

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  1. Palitantin (HB4012)

    Description:

    Metabolite of Penicillium with antiprotozoal and antifungal activity

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $227
    Qty:
  2. Palmarumycin C3 (HB4013)

    Description:

    Rasfarnesyltransferase inhibitor

    Purity:

    >97%

    Pack:
    5mg
    Price:
    $509
    Qty:
  3. Description:

    Spirobisnaphthalene derivative

    Purity:

    >96%

    Pack:
    5mg
    Price:
    $441
    Qty:
  4. Pam2CSK4 (HB3086)

    Description:

    TLR2/6 activator. Induces potent NF-κB activation and cytokine production.

    Pack:
    1mg
    Price:
    $157
    Qty:
  5. Pam3CSK4 (HB3428)

    Description:

    TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.

    Pack:
    1mg
    Price:
    $147
    Qty:
  6. Pack:
    10mg
    Price:
    $102
    Qty:
    Pack:
    50mg
    Price:
    $406
    Qty:
  7. Paxilline (HB1056)

    Description:

    Potent, reversible, selective KCa channel inhibitor. Also SERCA inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $147
    Qty:
  8. Pack:
    50mg
    Price:
    $529
    Qty:
  9. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    2mg
    Price:
    $28
    Qty:
    Pack:
    5×2mg
    Price:
    $115
    Qty:
    Pack:
    10mg
    Price:
    $109
    Qty:
    Pack:
    50mg
    Price:
    $308
    Qty:
  10. PD 102807 (HB1509)

    Description:

    Potent, selective M4 receptor antagonist. Promotes erythroid progenitors expansion.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $287
    Qty:
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