Endogenous lysophospholipid LPA1 and LPA2 receptor agonist. Inhibits differentiation of neural stem cells (NSCs) into neurons and is also commonly used for growth stimulation in a variety of cell lines.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in PBS (10mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Rho/ROCK pathway is essential to the expansion, differentiation, and morphological rearrangements of human neural stem/progenitor cells induced by lysophosphatidic acid
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.