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Okadaic Acid Sodium Salt

(HB0470)
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Product overview

Name Okadaic Acid Sodium Salt
Purity >98%
Description Water soluble, potent protein phosphatase 1 and 2A inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description Water soluble. Potent protein phosphatase 1 (PP1) and 2A (PP2A) inhibitor (IC50 values are 3 and 0.2-1 nM). Found in the black sponge Halichondria okadai. Mimics effects of insulin on glucose transport in adipocytes. Displays tumour promoting properties.

Solubility & Handling

Storage instructions

-20°C (desiccate)

Solubility overview Soluble in DMSO (1mg/ml) or ethanol
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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More Info

Dilution

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More Info

Chemical Data

Purity >98%
Molecular Weight 827
Chemical structure Okadaic Acid Sodium Salt [209266-80-8] Chemical Structure
Molecular Formula C44H67O13Na
CAS Number 209266-80-8
PubChem identifier 23714931
SMILES CC1CC[C@]2(CCCCO2)O[C@@H]1[C@@H](C)C[C@@H]([C@@H]3C(=C)[C@H]([C@H]4[C@H](O3)CC[C@]5(O4)CC[C@@H](O5)/C=C/[C@@H](C)[C@@H]6CC(=C[C@@]7(O6)[C@@H](CC[C@H](O7)C[C@](C)(C(=O)[O-])O)O)C)O)O.[Na+]

References for Okadaic Acid Sodium Salt

References are publications that support the biological activity of the product

  • Okadaic acid: a new probe for the study of cellular regulation.

    Cohen P et al (1990) Trends Biochem Sci 15(3) : 98-102.
    Read more (PubMedID: 2158158)

  • Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism.

    Haystead TA et al (1989) Nature 337(6202) : 78-81.
    Read more (PubMedID: 2562908)

  • Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics.

    Bialojan C et al (1988) Biochem J 256(1) : 283-90.
    Read more (PubMedID: 2851982)

3 Item(s)

Grouped product items
Order: HB0470
Pack PriceQty
100μg
$230
Water soluble, potent protein phosphatase 1 and 2A inhibitor
Shipping Info

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