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Okadaic Acid Sodium Salt

(HB0470)
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Technical documents: SDS CoA Datasheet
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Product overview

Name Okadaic Acid Sodium Salt
Purity >98%
Description Water soluble, potent protein phosphatase 1 and 2A inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description Water soluble. Potent protein phosphatase 1 (PP1) and 2A (PP2A) inhibitor (IC50 values are 3 and 0.2-1 nM). Found in the black sponge Halichondria okadai. Mimics effects of insulin on glucose transport in adipocytes. Displays tumour promoting properties.

Solubility & Handling

Solubility overview Soluble in DMSO (1mg/ml) or ethanol
Storage instructions

-20°C (desiccate)

Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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More Info

Dilution

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Chemical Data

Purity >98%
Molecular Weight 827
Chemical structure Okadaic Acid Sodium Salt [209266-80-8] Chemical Structure
Molecular Formula C44H67O13Na
CAS Number 209266-80-8
PubChem identifier 23714931
SMILES CC1CC[C@]2(CCCCO2)O[C@@H]1[C@@H](C)C[C@@H]([C@@H]3C(=C)[C@H]([C@H]4[C@H](O3)CC[C@]5(O4)CC[C@@H](O5)/C=C/[C@@H](C)[C@@H]6CC(=C[C@@]7(O6)[C@@H](CC[C@H](O7)C[C@](C)(C(=O)[O-])O)O)C)O)O.[Na+]

References for Okadaic Acid Sodium Salt

References are publications that support the biological activity of the product

  • Okadaic acid: a new probe for the study of cellular regulation.

    Cohen P et al (1990) Trends Biochem Sci 15(3) : 98-102.
    Read more (PubMedID: 2158158)

  • Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism.

    Haystead TA et al (1989) Nature 337(6202) : 78-81.
    Read more (PubMedID: 2562908)

  • Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics.

    Bialojan C et al (1988) Biochem J 256(1) : 283-90.
    Read more (PubMedID: 2851982)

3 Item(s)

Grouped product items
Order: HB0470
Pack PriceQty
100μg
$237
Water soluble, potent protein phosphatase 1 and 2A inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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