DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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Okadaic Acid (HB0468)
Description:Potent, non-competitive protein phosphatase inhibitor
Purity:>98%
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Okadaic Acid Sodium Salt (HB0470)
Description:Water soluble, potent protein phosphatase 1 and 2A inhibitor
Purity:>98%
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Olanzapine (HB1786)
Description:5-HT2A and D2 antagonist. Potent DREADD agonist. Atypical antipsychotic.
Purity:>99%
- Description:
LPA1 and LPA2 agonist. Inhibits differentiation of neural stem cells (NSCs) into neurons.
Purity:>95%
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ω-Agatoxin IVA (HB1212)
Description:Potent, selective P-type / Q-type Ca2+ channel blocker
Purity:>95%
