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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 1021-1030 of 1078

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  1. VU 0357017 hydrochloride (HB1498)

    Description:

    Potent, selective M1 receptor allosteric agonist

    Purity:

    >98%

    VU 0357017 hydrochloride
    Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    50mg
    Price:
    $691
    Qty:
    Supporting Docs Add to Favorites

  2. VU 0360223 (HB0637)

    Description:

    mGlu5 negative allosteric modulator

    Purity:

    >99%

    VU 0360223
    Pack:
    50mg
    Price:
    $495
    Qty:
    Supporting Docs Add to Favorites

  3. VU 0361737 (HB0638)

    Description:

    mGlu4 positive allosteric modulator

    Purity:

    >99%

    VU 0361737
    Pack:
    10mg
    Price:
    $121
    Qty:
    Pack:
    50mg
    Price:
    $475
    Qty:
    Supporting Docs Add to Favorites

  4. VU 0364439 (HB0639)

    Description:

    Potent mGlu4 positive allosteric modulator

    Purity:

    >99%

    VU 0364439
    Pack:
    50mg
    Price:
    $722
    Qty:
    Supporting Docs Add to Favorites

  5. VU 0364770 (HB0640)

    Description:

    mGlu4 positive allosteric modulator

    Purity:

    >99%

    VU 0364770
    Pack:
    50mg
    Price:
    $653
    Qty:
    Supporting Docs Add to Favorites

  6. VU 29 (HB0642)

    Description:

    Potent mGlu5 positive allosteric modulator

    Purity:

    >98%

    VU 29
    Pack:
    10mg
    Price:
    $153
    Qty:
    Pack:
    50mg
    Price:
    $630
    Qty:
    Supporting Docs Add to Favorites

  7. VX 702 (HB1308)

    Description:

    Potent, selective ATP-competitive p38 MAPK inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $156
    Qty:
    Supporting Docs Add to Favorites

  8. VX 745 (HB1309)

    Description:

    Potent, selective p38α MAPK inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $211
    Qty:
    Pack:
    50mg
    Price:
    $814
    Qty:
    Supporting Docs Add to Favorites

  9. W-5 hydrochloride (HB0649)

    Description:

    Calmodulin (CaM) antagonist

    Purity:

    >98%

    W-5 hydrochloride
    Pack:
    25mg
    Price:
    $266
    Qty:
    Supporting Docs Add to Favorites

  10. WAY 100635 maleate (HB1790)

    Description:

    Potent 5-HT1A receptor antagonist. D4 receptor agonist.

    Purity:

    >99%

    WAY 100635 maleate
    Pack:
    50mg
    Price:
    $693
    Qty:
    Supporting Docs Add to Favorites
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