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DREADD

Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

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  1. Prestained Protein Ladder (11 – 270 kDa) (HB9198)

    Description:

    Dual color broad range protein ladder

    Prestained Protein Ladder (11 – 270 kDa)
    Pack:
    500μL
    Price:
    $107
    Qty:
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  2. Anti-Calbindin antibody ValidAbâ„¢ (HB6396)

    Description:

    Antibody to Calbindin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Rat
    Figure 1. Calbindin and Calretinin expression in rat cerebellum
    Pack:
    25μg
    Price:
    $150
    Qty:
    Pack:
    100μg
    Price:
    $336
    Qty:
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  3. Anti-GluN1 antibody ValidAbTM (HB7535)

    Description:

    Antibody to the GluN1 subunit of the NMDA receptor. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Anti-GluN1 antibody ValidAb<sup>TM</sup>
    Pack:
    3μg
    Price:
    $131
    Qty:
    Pack:
    15μg
    Price:
    $457
    Qty:
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  4. Diphenhydramine hydrochloride (DPH) (HB2617)

    Description:

    Histamine H1 antagonist. Potent actuator of a modified hM4Di "GRANPA" DREADD receptor.

    Purity:

    >99%

    Pack:
    500mg
    Price:
    $54
    Qty:
    Pack:
    1g
    Price:
    $75
    Qty:
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  5. Western Blot Stripping Buffer (HB7756)

    Description:

    Buffer for stripping of chemiluminscent Western blots

    Figure 1. Stripping and re-probing of PVDF membrane using HB7756
    Pack:
    500mL
    Price:
    $116
    Qty:
    Pack:
    2x500mL
    Price:
    $185
    Qty:
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  6. 10x Western Blot Stripping Buffer (HB9167)

    Description:

    10x buffer for stripping of chemiluminescent Western blots

    Figure 1. Stripping and re-probing of PVDF membrane using HB9167
    Pack:
    500mL
    Price:
    $271
    Qty:
    Pack:
    2x500mL
    Price:
    $406
    Qty:
    Supporting Docs Add to Favorites

  7. SuperBlotTM ECL Western Blotting Substrate Kit (High sensitivity) (HB9308)

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    Description:

    High sensitivity ECL solution for developing chemiluminescent Western blots

    Figure 1. Representative blots for Neurofilament L of SuperBlot<sup>TM</sup> ECL Western Blotting Substrate Kit (High sensitivity) and competitor solutions
    Pack:
    100mL
    Price:
    $165
    Qty:
    Pack:
    250mL
    Price:
    $225
    Qty:
    Pack:
    500mL
    Price:
    $413
    Qty:
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  8. SuperBlotTM ECL Western Blotting Substrate Kit (Standard) (HB7090)

    Description:

    Standard sensitivity ECL solution for developing chemiluminescent Western blots

    Figure 3. GAPDH Western Blot exposed using SuperBlot<sup>TM</sup> ECL Western Blotting Substrate Kit (Standard)
    Pack:
    100mL
    Price:
    $110
    Qty:
    Pack:
    250mL
    Price:
    $170
    Qty:
    Pack:
    500mL
    Price:
    $314
    Qty:
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  9. Janelia Fluor® 525 conjugation kit (HB9768)

    Description:

    Kit for conjugation of antibodies and other proteins to Janelia Fluor® 525

    Figure 1. Janelia Fluor 525 conjugated anti-Myelin Basic Protein antibody staining in rat cerebellum
    Pack:
    2 x 50μg
    Price:
    $270
    Qty:
    Pack:
    3 x 100μg
    Price:
    $473
    Qty:
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  10. Janelia Fluor® 549 conjugation kit (HB9660)

    Description:

    Kit for conjugation of antibodies and other proteins to Janelia Fluor® 549

    Figure 1. Janelia Fluor 549 conjugated anti-NeuN antibody staining in rat hippocampus
    Pack:
    2 x 50μg
    Price:
    $275
    Qty:
    Pack:
    3 x 100μg
    Price:
    $473
    Qty:
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Category
Biological action
  1. Inducer
  2. Metabolite
  3. Modulator
  4. Reagent
  5. Toxin
  6. Agonist
  7. Antagonist
  8. Activator
  9. Buffer
  10. Kit
  11. Inhibitor
  12. Blocker
  13. PAM
  14. NAM
  15. Substrate
  16. Chelator
  17. Caged compound
  18. Peptide
  19. Ionophore
  20. Dyes & stains
  21. Other
Applications
  1. Antineoplastic Agent
  2. Cell Culture
  3. ELISA
  4. FACS and flow cytometry
  5. fluorescence imaging
  6. ICC
  7. IF
  8. IHC
  9. live cell imaging
  10. Plant Culture
  11. Selection Agent
  12. WB
  13. IHC(IF)
  14. Histoblot
  15. SDS-PAGE
Host
  1. Mouse
  2. Rabbit
  3. Goat
  4. Chicken
Conjugate
  1. Horseradish peroxidase (HRP)
Target
  1. D1
  2. GluN1
  3. GFAP
  4. GAPDH
  5. NeuN
  6. mCherry
  7. Neurofilament L
  8. Beta III tubulin
  9. HSP60
  10. Neurofilament M
  11. GFP
  12. MAP2
  13. Tyrosine hydroxylase
  14. β-tubulin
  15. Myelin basic protein
  16. GAT1
  17. c-Fos
  18. Vimentin
  19. BrdU
  20. Mouse IgG H&L
  21. Rabbit IgG H&L
  22. GST tag
  23. VGAT
  24. Parvalbumin
  25. Calretinin
  26. Calbindin
  27. Histone H3
  28. Ki-67
  29. IBA1
  30. mTOR
  31. Chicken IgY H&L