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Diphenhydramine hydrochloride (DPH)

(HB2617)
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Product overview

Name Diphenhydramine hydrochloride (DPH)
Purity >99%
Description

Histamine H1 antagonist. Potent actuator of a modified hM4Di "GRANPA" DREADD receptor.

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (2) Reviews References (2)
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Biological Data

Biological description

Histamine H1 antagonist. Potently activates the modified hM4Di "GRANPA" (G protein Receptor Activated by Non-Presciption Agents) DREADD receptor in vitro and in vivo.

Solubility & Handling

Storage instructions Room temperature, desiccate.
Solubility overview Soluble in water (100 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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More Info

Dilution

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Chemical Data

Purity >99%
Chemical name 2-Diphenylmethoxy-N,N-dimethylethanamine hydrochloride
Molecular Weight 291.82
Chemical structure Diphenhydramine [147-24-0] Chemical Structure
Molecular Formula C17H21NO.HCl
CAS Number 147-24-0
PubChem identifier 8980
SMILES CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
InChi InChI=1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H
InChiKey PCHPORCSPXIHLZ-UHFFFAOYSA-N
MDL number MFCD00012479
Appearance White solid

References for Diphenhydramine hydrochloride (DPH)

References are publications that support the biological activity of the product

  • Improving the suitability of chemogenetic gene therapies by repurposing non-prescription agents as actuators

    Devenish et al (2022) Ucl Neuroscience Symposium 2022 :

  • Classic histamine H1 receptor antagonists: a critical review of their metabolic and pharmacokinetic fate from a bird's eye view.

    Sharma A et al (2003) Current drug metabolism 4 : 105-29
    Read more (PubMedID: 12678691)

2 Item(s)

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Grouped product items
Order: HB2617
Pack PriceQty
500mg
$54
1g
$75

Histamine H1 antagonist. Potent actuator of a modified hM4Di "GRANPA" DREADD receptor.

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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