G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Haloperidol hydrochloride (HB1842)
Description:Dopamine receptor antagonist with partial D2-like selectivity
Purity:>99%
Kainic acid (HB0355)
Description:Prototypic, selective kainate receptor agonist. Potent excitant and neurotoxin.
Purity:>98%
(+)-MK 801 maleate (HB0004)
Description:Potent, selective, non-competitive NMDA receptor antagonist
Purity:>98%
MOG (35-55) (HB5273)
Description:Myelin oligodendrocyte glycoprotein fragment. Induces experimental multiple sclerosis-like disease.
Purity:>95%
MPEP hydrochloride (HB0426)
Description:Potent, selective mGluR5 antagonist / mGluR4 positive allosteric modulator
Purity:>98%