Myelin oligodendrocyte glycoprotein fragment which is a component of CNS myelin. Induces experimental multiple sclerosis-like disease and induces T-cell mediated multiple sclerosis models. Also induces tolerogenic dendritic cells and supresses disease development in multiple sclerosis models when co-administered with ITE.
Solubility & Handling
Solubility overview
Soluble in water (1 mg/ml)
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
References are publications that support the biological activity of the product
Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis.
Haas J et al (2005) European journal of immunology 35 : 3343-52
Understanding purity and quality - a guide for life scientists
