G protein coupled receptors

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G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

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    Description:

    Neurotoxin, widely used to produce the 6-OHDA Parkinson’s disease model

    Purity:

    >98%

    Pack:
    50mg
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    $62
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    250mg
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    $116
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    1g
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    $391
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    100μg
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    $97
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    500μg
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    $161
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    1mg
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    $299
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    50mg
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    $162
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    10mg
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    $66
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    50mg
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    $256
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    10mM (add 1ml water)
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    $58
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    25mg
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    $156
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    50mg
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    $307
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    125mg
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    $556
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    25mg
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    $191
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    50mg
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    $373
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    125mg
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    $686
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  7. Cyclosporin A (HB0220)

    Description:

    Potent calcineurin inhibitor. Inhibits MPTP opening.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $96
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