G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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PNU 74654 (HB0528)
Description:β-catenin inhibitor. Wnt pathway inhibitor. Promotes neural differentiation of hPSCs.
Purity:>99%
PPDA (HB0531)
Description:Potent GluN2C / GluN2D subunit selective NMDA receptor antagonist
Purity:>98%
PS-341 [Bortezomib] (HB4036)
Description:Highly potent, selective, reversible and cell permeable proteasome inhibitor
Purity:>98%