PS-341 [Bortezomib] product vial image | Hello Bio
PS-341 [Bortezomib] product vial image | Hello Bio
Biological Data
Biological description
Highly potent, selective and reversible cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome. Calpain and cathepsin inhibitor. Autophagy activator. Anticancer compound. Inhibits proliferation and migration of several tumor cell lines with nanomolar potency. Apoptosis inducer.
Solubility & Handling
Storage instructions
+4°C
Solubility overview
DMSO (100mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells
Fribley et al (2004) Mol Cell Biol 24(22) : 9695-704.
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