PP 2 (Src kinase inhibitor) negative control. Does not inhibit Src family kinases. Inhibits EGFR kinase and CK1δ (IC50 values are 2.7 and 9.9 µM respectively).
Solubility & Handling
Solubility overview
Soluble in DMSO (100mM) or ethanol (25mM)
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173.
Kong L et al (2011) Mol Cell Biochem 348(1-2) : 11-9.
Understanding purity and quality - a guide for life scientists