GluN2

Potent, selective Ca_v2.2 (N-type) channel blocker

N-, P- and Q-type voltage-dependent Ca²⁺ channel blocker

Endogenous gluococorticoid. MR and GR agonist.

Potent, non-competitive AMPA receptor antagonist

Potent JAK inhibitor

Synthetic GP inhibitor

Potent, selective 5-HT_1B receptor agonist

Selective, non-competitive mGlu₁ antagonist

Potent, selective, competitive NMDA receptor antagonist

Potent NMDA receptor antagonist