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CP 94253 dihydrochloride

(HB1671)
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Product overview

Name CP 94253 dihydrochloride
Purity >98%
Description Potent, selective 5-HT1B receptor agonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (4) Frequently bought together
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Biological Data

Biological description Potent, selective 5-HT1B receptor agonist (Ki values are 2, 89, 49, 860, and 1600 nM at 5-HT1B, 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 respectively). Reduces foot intake, anticonvulsant and antidepressant-like effects. Active in vivo. Blood-brain barrier permeable.

Solubility & Handling

Solubility overview

Soluble in water (15mM) amd DMSO (100mM)

Storage instructions

Room temperature (desiccate)

Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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More Info

Dilution

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Chemical Data

Purity >98%
Chemical name 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine dihydrochloride
Molecular Weight 330.3
Chemical structure CP 94253 hydrochloride [845861-39-4] Chemical Structure
Molecular Formula C15H19N3O.2HCl
CAS Number 845861-39-4
PubChem identifier 11652258
SMILES Cl.CCCOC1=CC=C2NC=C(C2=N1)C1=CCNCC1
InChiKey PIIOXKQIZCVXMD-UHFFFAOYSA-N
Appearance Pale yellow solid

References for CP 94253 dihydrochloride

References are publications that support the biological activity of the product

  • Effect of 5-HT1B receptor agonists injected into the prefrontal cortex on maternal aggression in rats.

    Veiga CP et al (2007) Braz J Med Biol Res 40(6) : 825-30.
    Read more (PubMedID: 17581682)

  • Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice.

    Wesołowska A et al (2006) Eur J Pharmacol 541(1-2) : 57-63.
    Read more (PubMedID: 16765343)

  • Antidepressant-like effect of the selective 5-HT1B receptor agonist CP 94253: a possible mechanism of action.

    Tatarczyńska E et al (2005) Eur J Pharmacol 516(1) : 46-50.
    Read more (PubMedID: 15913599)

  • Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253

    Koet et al (1992) Drug dev res 26(3) : 241-250

4 Item(s)

Related Products
Grouped product items
Order: HB1671
Pack PriceQty
10mg
$140
50mg
$574
Potent, selective 5-HT1B receptor agonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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