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ω-Conotoxin MVIIC

(HB1219)
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Technical documents: SDS CoA Datasheet
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Product overview

Name ω-Conotoxin MVIIC
Purity >99%
Special requirements

As this product is a toxin, customers are required to complete a short end user declaration when ordering. Our customer care team will be happy to help you with this.

This is a home office notifiable schedule 5 toxin.

Description N-, P- and Q-type voltage-dependent Ca2+ channel blocker
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description Cav2.1 (P/Q-type) and Cav2.2 (N-type) voltage-dependent Ca2+ channel blocker. Peptide neurotoxin.

Solubility & Handling

Solubility overview Soluble in water (1mg/ml)
Storage instructions -20°C (desiccate)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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x
x
More Info

Dilution

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x
More Info

Chemical Data

Purity >99%
Chemical name H-Cys(1)-Lys-Gly-Lys-Gly-Ala-Pro-Cys(2)-Arg-Lys-Thr-Met-Tyr-Asp-Cys(3)-Cys(1)-Ser-Gly-Ser-Cys(2)-Gly-Arg-Arg-Gly-Lys-Cys(3)-NH2
Molecular Weight 2749
Molecular Formula C106H178N40O32S7
CAS Number 147794-23-8
PubChem identifier 56841670
SMILES C[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@H]3CSSC[C@H]4C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N4)CO)CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC3=O)CCCNC(=N)N)CCCCN)[C@@H](C)O)CCSC)CC5=CC=C(C=C5)O)CC(=O)O)C(=O)N)CCCCN)CCCNC(=N)N)CCCNC(=N)N
InChi InChI=1S/C106H178N40O32S7/c1-53-103(178)146-36-15-23-75(146)101(176)144-74-52-185-183-49-71-89(164)126-43-79(154)130-62(21-13-34-120-105(115)116)90(165)133-60(20-12-33-119-104(113)114)87(162)124-42-78(153)129-61(18-6-10-31-109)91(166)140-70(83(112)158)48-
InChiKey FHVUTHWUIUXZBY-QLANQDRJSA-N
MDL number MFCD00214640

References for ω-Conotoxin MVIIC

References are publications that support the biological activity of the product

  • Omega-conotoxin MVIIC attenuates neuronal apoptosis in vitro and improves significant recovery after spinal cord injury in vivo in rats.

    Oliveira KM et al (2014) Int J Clin Exp Pathol 7(7) : 3524-36.
    Read more (PubMedID: 25120731)

  • Inhibition of calcium channels in rat central and peripheral neurons by omega-conotoxin MVIIC.

    McDonough et al (1996) J Neurosci 16(8) : 2612-23
    Read more (PubMedID: 8786437)

  • Identification of three subunits of the high affinity omega-conotoxin MVIIC-sensitive Ca2+ channel.

    Liu H et al (1996) J Biol Chem 271(23) : 13804-10.
    Read more (PubMedID: 8662888)

3 Item(s)

Related Products
Grouped product items
Order: HB1219
Pack PriceQty
100μg
$204
500μg
$710
N-, P- and Q-type voltage-dependent Ca2+ channel blocker
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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