Ionotropic glutamate receptors
Ionotropic glutamate receptors (NMDA, AMPA and Kainate receptors) are cation-selective tetramers formed by multimeric assemblies of subunits. AMPA receptors comprise of homomers or heteromers of GluA1, GluA2, GluA3 and GluA4 subunits. NMDA receptors are heteromic assemblies of GluN1, GluN2A, GluN2B, GluN2C, GluN2D, GluN3A and GluN3B. Kainate receptors can be expressed as homomers of GluK1, GluK2 or GluK3. Researchers can save up to 50% on potent & selective NMDA, AMPA and Kainate receptor antagonists, agonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View resources: Ionotropic Receptor Nomenclature Guide | NMDA Receptor Mini-Review | NMDAR Associated Proteins
View products:Â AMPA | Kainate | NMDA
Recombinant human GDNF protein (HB5735)
Description:Neurotrophin which enhances differentiation and survival of dopaminergic neurons
-
Recombinant human NT-3 protein (HB8373)
Description:Neurotrophin involved in neuron development, survival and differentiation
-
RepSox (HB3301)
Description:Potent, selective TGF-βRI inhibitor. Enhances cellular reprogramming efficiency.
Purity:>99%
-
RG 108 (HB1377)
Description:Non-nucleoside DNA methyltransferase inhibitor. Enhances iPSC generation efficiency.
Purity:>99%
-
Rosiglitazone (HB2556)
Description:Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.
Purity:>99%
-
SAG (HB3107)
Description:Cell permeable Sonic hedgehog (Shh) agonist and Smo agonist. Enhances neuronal differentiation of iPSC into dopaminergic neurons.
Purity:>98%
-
SB 202190 (HB1301)
Description:Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.
Purity:>99%
-
SB 203580 (HB1302)
Description:Potent, selective p38 MAPK inhibitor. Stimulates neural stem cell proliferation.
Purity:>98%
-
SB 216763 (HB1272)
Description:Potent, selective cell permeable GSK-3 inhibitor. Maintains mESCs and promotes retinal stem cells proliferation.
Purity:>98%
-
SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
