5-HT3

Non-competitive, GluN2B subunit selective NMDA receptor antagonist

Potent GABA_A receptor positive allosteric modulator

Potent AMPA / kainate receptor antagonist. Vesicular L-glutamate uptake inhibitor.

Selective L-type VOCC blocker

Potent, selective MDR receptor agonist

GABA_A receptor antagonist

Endogenous inhibitory neurotransmitter

Broad spectrum glutamate antagonist

Glutamate receptor excitatory neurotransmitter

Endogenous NMDA receptor excitatory amino acid