Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Pack:
    50mg
    Price:
    $529
    Qty:
  2. Pack:
    10mg
    Price:
    $116
    Qty:
    Pack:
    50mg
    Price:
    $327
    Qty:
  3. Pack:
    50mg
    Price:
    $45
    Qty:
    Pack:
    250mg
    Price:
    $77
    Qty:
    Pack:
    1g
    Price:
    $125
    Qty:
  4. Splitomicin (HB4091)

    Description:

    Potent,selective, cell permeable yeast NAD+-dependent HDAC Sir2p inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $359
    Qty:
  5. Pack:
    50mg
    Price:
    $922
    Qty:
  6. Trichostatin A (HB1402)

    Description:

    Potent HDAC inhibitor. Induces hiPSCs differentiation to cardiogenic cells and induces accelerated dedifferentiation of primordial germ cells.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $296
    Qty:
  7. Description:

    Histone deacetylase inhibitor. Shows multitude of biological actions. Enables pluripotent stem cell induction from somatic cells.

    Pack:
    10g
    Price:
    $51
    Qty:
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